ReBalance® Oral Suspension Santa Cruz Animal Health
Equine Protozoal Myeloencephalitis (EPM) is an infectious disease of the horse's central nervous system.. It is one of the most difficult diseases for veterinarians to diagnose because it often mimics other conditions and has a wide range of symptoms that affect multiple parts of the horse's body.. Horses affected by EPM may show a lack of coordination in their movements, usually worse on.
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Prior to treatment with ReBalance ® Antiprotozoal Oral Suspension, EPM should be distinguished from other diseases that may cause ataxia in horses. Injuries or lameness may also complicate the evaluation of an animal with EPM. In most instances, ataxia due to EPM is asymmetrical and affects the front and/or the hind limbs.
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ReBalance is an FDA-approved, safe and effective treatment for horses with equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona. The active ingredients (Sulfadiazine 250mg/ml and pyrimethamine 12.5mg/ml) inhibit folic acid synthesis at two different sites, in the same synthetic pathway. 32oz bottle.
ReBalance® Oral Suspension Santa Cruz Animal Health
EPM is one of the more common neurological infectious diseases of horses in North America, but the disease may be seen in Europe in imported horses. Most cases are caused by Sarcocystis neurona and less commonly Neospora hughesi, both protozoan apicomplexan parasites. ReBalance ® Antiprotozoal Oral Suspension is indicated for the treatment of.
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Updated May 8, 2023. Equine Protozoal Myeloencephalitis (EPM) is a disease of the central nervous system (brain and spinal cord) caused by the protozoa Sarcocystis neurona. EPM is transmitted by the opossum through intermediate hosts, also known as carriers, which may include birds, cats, and other animals.
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Forty-eight horses were assigned to the 20 mg sulfadiazine/kg and 1 mg pyrimethamine/kg dose of REBALANCE Antiprotozoal Oral Suspension (1X treatment group). The final database consisted of 26 horses treated at the 1X dose, the other 22 horses in the 1X group failing to complete the study. Day 0 was the day the horse was first administered test
REBALANCE Antiprotozoal Oral Suspension for Horses, 1qt
Phone: 800-934-9398. Fax: 844-334-5653. Email: [email protected]. HeartlandVetSupply. 401 W. 33rd Street. Hastings, NE 68901. Price Match Guarantee. Rebalance is an FDA-approved, safe and effective treatment for horses with equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona.
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ReBalance is an oral suspension for horses with equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona. EPM is a nervous system disease that horses develop by ingesting contaminated feedstuffs with the protozoa Sarcocystis neurona. EPM presents highly variable clinical signs that may range from head tilt, ear droop, blindness.
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The safe use of ReBalance Antiprotozoal Oral Suspension in horses used for breeding purposes, during pregnancy, or in lactating mares has not been evaluated. The safety of ReBalance with concomitant therapies in horses has not been evaluated. ReBalance is not for use in horses with known hypersensitivity to sulfonamide drugs or pyrimethamine.
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EPM is a nervous system disease developed by horses when ingesting contaminated feed or water with the protozoa sarcocystis neurona. Each ml of ReBalance Antiprotozoal oral suspension contains 250 mg of sulfadiazine and 12.5 mg pyrimethamine. The usual treatment regimen varies from 90 to 270 days. Labeled for: horses. Species: horse.
ReBalance® Oral Suspension Santa Cruz Animal Health
• Pyrimethamine and sulfadiazine (tradename Rebalance), an oral suspension administered once daily for as long as 120 days. • Diclazuril (tradename Protazil), a pelleted, alfalfa-based top-dressing fed for 28 days.. Then horses are infected with intravenous injections, but this skips several stages of natural infection, which may mean.
REBALANCE Antiprotozoal Oral Suspension for Horses, 1qt
The safety of ReBalance ® Antiprotozoal Oral Suspension with concomitant therapies in horses has not been evaluated. Adverse Reactions. Seventy-five horses (37 horses in the 1X group; 38 horses in the 2X group) that were treated with test article for at least 90 days were evaluated for adverse reactions. Bone marrow suppression:
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Ninety-seven horses were randomly assigned to one of two treatment groups and administered a daily oral dose of ReBalance® Antiprotozoal Oral Suspension for a minimum of 90 days. The two treatment groups were as follows: (1) 1X labeled dose, 20 mg/kg sulfadiazine and 1 mg/kg pyrimethamine (48 horses); or. (2) 2X dose, twice the labeled dose.
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When administered under labeled conditions, ReBalance is an FDA-approved, safe and effective treatment for horses with equine protozoal myeloencephalitis ( EPM ) caused by Sarcocystis neurona. Product Information Manufactured for PRN Pharmacal. Active Ingredients Sulfadiazine 250mg/mL, Pyrimethamine 12.5mg/mL Direction
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Typical treatment regimens last between 90 and 270 days. Use a suitable syringe to administer orally a minimum of 1 hour before feeding grain or hay. Insert the syringe nozzle through the interdental space. Depress the plunger to deposit onto the back of the tongue. Follow your veterinarian's directions for use.
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Published by Clayton Newton on November 28, 2022. ReBalance Antiprotozoal Oral Suspension is for oral use only in horses. The usual duration of treatment is dependent on clinical response, but the usual treatment regimen ranges from 90 to 270 days.